Q: What are the symptoms of thrombosis with thrombocytopenia syndrome (TTS) following Janssen COVID-19 vaccine?

A rare adverse event has been reported through the Vaccine Adverse Events Reporting System (VAERS). Cerebral venous sinus thrombosis (CVST) has been reported after viral vector vaccines (J&J and Astra-Zeneca). Symptoms for CVST and blood clots include severe headache, blurry vision, shortness of breath, fainting, loss of consciousness, and weakness. The incidence of CVST or thrombocytopenia following vaccination is much less than from a COVID infection, birth control pills, smoking, or heparin therapy.

Response by Jeffrey Kuhlman, MD, Senior Vice President and Chief Quality and Safety Officer, AdventHealth